Bone Disease

Bone disease is a disorder that damages the skeleton and the bones weak and vulnerable to fracture. Weak bones are not a normal part of aging. While strong bones begin in childhood, people of all ages can improve their bone health.

The most common bone disease is osteoporosis, which is characterized by low bone mass and deterioration of bone structure. Osteoporosis can be prevented and diagnosed and treated. Low bone mass is when bones lose minerals such as calcium, making them strong, and therefore, bones become weak and fracture. Fractures of weak bones usually occur from falling or other accidents common.

Other bone diseases include Paget's disease and osteogenesis imperfecta. Paget's disease affects older men and women, and causes skeletal deformities and fractures. Osteogenesis imperfecta is an inherited disease that causes brittle bones and frequent fractures in children.

A skeletal health system with strong bones is essential to overall health and quality of life. Strong bones support our bodies protect our heart, lungs and brain injury, and provide the framework for the muscles that allow us to move. Bones are also a storehouse for minerals sustain life.

Osteoporosis and bone diseases such as Paget's disease and osteogenesis imperfecta, can lead to a downward spiral in physical health and quality of life, including losing the ability to walk, stand, and dress . It can even lead to premature death. Weak bones can lead to painful and debilitating fractures. Each year, 1.5 million Americans suffer a bone fracture, as weak. Breaks the most common are the wrist, spine and hip.

Hip fractures are by far the most devastating type of broken bone and accounts for nearly 300,000 hospitalizations each year. Of hip fracture patients: 20 percent die within one year after the fracture, and 20 percent end up in a retirement home in a year. Many become isolated, depressed or afraid to leave home because they are afraid of falling.

Bone disease is costly to society and individuals with the disease. In the U.S., care for bone fractures from osteoporosis costs nearly $ 18 billion annually. The cost of a hip fracture for an individual may be more than $ 81 000 during their life.

Many Americans are unaware that their bone health is in danger. Osteoporosis is a silent disease until fractures occur. Four times as many men and nearly three times as many women have osteoporosis than report having the disease. The number of hip fractures in the United States could double or even triple by 2040. Bone disease affects women and men of all ethnic groups, although the risk of bone disease is higher among women. Bone disease is a real risk to any man or woman at any age.
Learn More type of Bone Disease - causes, symptoms and treatment :

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Two genes of adiposity are associated with type II diabetes

Genetic studies of association earlier suggested a strong link between genes MSRA (methionine sulfoxide reductase A), LYPLAL1 (Lysophospholipase-like protein 1) and TFAP2B (transcription factor activating enhancer binding protein 2 beta), and adiposity of abdomen (fatty condition of the latter). Sulfoxide reductase A methionine is an enzyme that reduces oxidative stress (aggression components of the cell due to reactive oxygen species), or the increased oxidative stress is responsible for the destruction of pancreatic beta cells that leads to the development of diabetes Type II. Similarly, Lysophospholipase-like protein 1 regulates the metabolism (mobilization and storage) fatty acids, while the increase in the flow of these fatty acids increase the risk of developing type II diabetes. TFAP2B protein was associated with insulin resistance in adolescents and type II diabetes in adults. Thus, an American team has looked for nucleotide variations in these genes in patients with type II diabetes in order to high light their involvement in this disease.

They showed that a variant in the gene associated MSRA was a significant risk of developing type II diabetes but only in men. Moreover, this genetic alteration is associated, in women, at a lower rate of adiponectin, a protein produced by adipose tissue that has an anti-diabetes by increasing insulin sensitivity. Furthermore, this decrease is often observed in obesity. The variant found in the gene is only weakly LYPLAL1 associated with type II diabetes. However, genetic variation in the gene identified TFAP2B is not associated with type II diabetes but is associated with leptin levels much lower and thus more appetite important.Cette a landmark study suggests that the gene and LYPLAL1 MSRA, two genes of abdominal adiposity, predispose to type II diabetes in humans. Subsequent studies identified will have their mechanisms of action in the development of type II diabetes.

Novel genes abdominal adiposity and the risk of type 2 diabetes: Findings from Two Prospective Cohorts. Yeung E, Qi L, Hu FB, Zhang C. Int J Mol Genet Epidemiol. 2011; 2 (2) :138-44.

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Red clover and menopause

 Health Care : The effects of red Treffle on menopausal symptoms were evaluated in 109 women aged 40 and older, who took for 90 days, 160 mg of red clover isoflavones per day (group A) or placebo with the same aspect (group B). After 7 days of withdrawal, treatment and placebo were interchanged without the knowledge of groups and taken for 90 days. The frequency of hot flashes and night sweats, and the intensity of menopausal symptoms (Kupperman Index index) were measured on days 0, 90, 97 and 187.

On day 0 (before treatment), the values ​​were identical between the two groups. In group A, all indices were significantly decreased compared to group B, after the first 90 days of treatment. During the seven days of weaning indices rebounded from group A while those of group B remained unchanged. After reversing the treatments, the indices of group B decreased significantly while the values ​​of group A remained similar to the weaning period. No side effects have been felt by study participants.

The effect of red clover isoflavone supplementation over and menopausal vasomotor symptoms in postmenopausal women. Lipovac M, P Chedraui, Gruenhut C, Gocan A, Kurz C, Neuber B, Imhof M. Gynecol Endocrinol. March 2012, 28 (3) :203-7.

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Pharyngitis and acute

Pharyngitis and acute infection, bacteria and viruses, is a disease would swelling is inflamed pharyngeal mucosa are stimulated by dirty air. 
It can also be checked by opening the mouth in front of the mirror, you will feel pain as well as when you swallowed foreign body sensation in the throat, sore throat, things. Clean, it is necessary to keep the cleanliness of the throat lozenges such as medicine and gargle frequently. Inflammation is suppressed by anti-inflammatory enzymes, bacteria and viruses if infection is treated with antibiotics.

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strep throat symptoms

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Group A Hemolytic Streptococcus Pharyngitis

Group A hemolytic streptococcus, commonly found in Gram-positive bacteria as the causative bacteria such as skin infections and suppurative inflammation of the upper airway, causing a variety of clinical symptoms and tissue site of invasion by bacteria.Disease can be seen daily as well, in addition to acute pharyngitis, scarlet fever as there is a special type disease impetigo, or cellulitis flame. Cause otitis media, pneumonia, septic arthritis, osteomyelitis, meningitis, etc. In addition to these. In addition, rather than the direct action of bacteria, that through the immunological mechanism, cause rheumatic fever and acute glomerulonephritis are known. In addition, the pathogenesis, pathophysiology is unknown, accompanied by soft tissue necrosis, (streptococcal toxic shock syndrome) is a serious disease problem as hemolytic streptococcus infection causing fulminant septic shock is. Here, in infectious disease surveillance under the Infectious Diseases Control Law, we describe the group A hemolytic streptococcus pharyngitis has become a fixed point understanding disease type 4 infection.


Epidemiology
of group A hemolytic streptococcus infection in temperate regions is a universal disease, but also found in subtropical regions, in tropical regions is a rare disease.


Hemolytic group A streptococcal pharyngitis, but can also occur in any age, most children of school age, in adults under the age of 3 cases and exhibits a typical clinical picture is small. According to the surveillance data of infectious diseases, the peak of the number of reports of two early summer has been observed from winter and spring. In recent years, there is a tendency to increase the overall number of reports, there is a possibility due to diagnostic technology has improved such as the spread of rapid diagnostic kit.
This disease is usually, in order to propagate through contact with the patient, the likelihood of contact when the opportunity to increase between people, many of infection in a group home, and schools. Infectious during the acute phase most strongly, and then gradually diminished. For the acute phase of infection rate between the brothers is the most high percentage, 25% have been reported. According to the studies using throat culture at the school, has been reported as 15 to 30% healthy carrier, it is believed that infection from healthy carrier is rare.

Pathogen
Streptococcus is a Gram-positive cocci, group Lancefield A ~ V (I, J are excluded) are classified according to antigenicity of the polysaccharides of the cell wall. Causative agent of this disease belongs to a group A of this, because it causes (complete hemolysis) β hemolysis on sheep blood agar added red blood cells, called β-hemolytic streptococcus group A (Streptococcus) hemolysis (α is incomplete hemolysis hemolysis, γ refers to a non-hemolytic). As the name of the fungal species (Streptococcus pyogenes Streptococcus pyogenes ) is used. Most of the hemolytic streptococcus group A has an M protein and T protein as an antigen protein on the cell surface, the antigenicity of these are further classified by type. To more than 100 M protein type, the T is a type of protein has been known about 0 to 5. In addition, it is believed that this fungus is secreted outside the cells by toxin-producing hemolysis, pyrogenic toxin (erythrogenic toxin), nucleic acid degrading enzymes, such as streptokinase, a protein agent various active, and cause various symptoms.

Clinical symptoms incubation period is a two to five days, about the infection in the incubation period is unknown. Developed sudden onset of fever and general malaise, by sore throat, often accompanied by vomiting. Pharyngeal wall is accompanied by leaching in the form of swelling tonsils, small strawberry tongue or soft palate petechiae. 

Case of scarlet fever, and 12 to 24 hours after the start of point-like fever-like skin rash erythema, sunburn-like occurrences (Photo 2) . The rash of large head needle, (sandpaper rash) to give a touch of the skin like sandpaper. Some (Pastia's sign) may appear to many parts of the wrinkles of the skin axilla, groin, etc. In particular, as they contain along this line. (Circumoral pallor) in facial skin rash that usually are not seen like this, forehead and cheeks flushed, looks only pallor around the mouth is characterized by (Photo 2) . In addition, as the change of tongue, early onset (white strawberry tongue) was observed tongue was covered with white moss, strawberry tongue and become (red strawberry tongue) and then peeling white moss. Membranous desquamation of the skin starts from the face from around the end of the first week, spread to all parts of the body before the third week.

As a complication, it may cause a non-suppurative disease rheumatic fever, acute glomerulonephritis, such as pneumonia, meningitis, or suppurative disease such as sepsis.

Pathogen diagnosis 
Is fundamental, but the bacteria can be separated by a throat culture, rapid diagnostic kit can also be used to detect the antigen polysaccharide group A. Sensitivity is equal to or greater than 80% specificity of rapid diagnostic kit is also generally high, because it depends on the amount of bacteria that is the amount of antigen, the data collection method is important monosaccharide pharynx.

Serological methods are available to see the rise of such antibody (ASK) antibody anti-streptolysin-O (ASO), anti-streptokinase antibody, become a reference for the diagnosis.

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Herbs, berries, nuts, honey, bee products, pepper for sore throat

Strep Throat Symptoms. a popular treatment for a sore throat. If you have a sore throat and a fever, you should immediately consult a doctor because it may very well be that you became ill with angina and angina - severe infectious disease, the treatment which some folk remedies are not enough. Angina can be a complication to the heart and joints, and then cope with the disease will be much harder, so do not delay! In addition, a sore throat at high temperature may be a symptom of diseases such as diphtheria, scarlet fever, whooping cough, and deal with them yourself you can not, do not even try. This is primarily a childhood disease, and if you do not want to ruin your child immediately if sore throat and temperature, call your doctor! Only tests will allow accurate diagnosis, and only a doctor can prescribe the right treatment. Folk remedies will help you quickly recover, but to preserve the health and sometimes lives, they are not enough! Here this you can do ;

  • Take 50 grams of the roots of elecampane, Y2 pour liters of vodka and leave for 3 days. Must be some Y3 teaspoon pour down your throat so that the infusion covered and left and right gland. A little cough. You can not drink water, it is also desirable not to talk with anyone that day. The procedure is done every hour until your health is restored. 
  • Take 1 tbsp. a spoonful of green walnut skin, pour 1 cup of warm water and add 1 tbsp. a spoonful of honey. Gargle 5-6 times a day. 
  • Prepare the infusion of chamomile flowers 1:10, why pick in '25 (6 CT. Tablespoons) dried flowers, fill them in enamelware 500ml boiling water, cover and set for 15 minutes in a boiling water bath. Then let the infusion cool down, strain it, and squeeze the remaining material and bring the volume of boiling water to 500 ml. Dissolve it in 2 tbsp. spoons of honey and use it to rinse for sore throat, stomatitis, and other diseases of the mouth and throat. 

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How quickly get clear skin - how to eat apples can clear your acne within days

When it comes to learning how to quickly get a clear skin, acne sufferers are ready for all kinds of crazy sums of money in the hope that they finally skinned. What is the usual result? Some improvement, but away from the skin without acne that most products promise. What is the problem? Why are so many products?
This is because these products treat acne as a skin problem. Acne is and always will be a problem that starts and stops inside your body. It is caused by things like massive insulin response to poor nutrition , hormonal responses called androgens when our blood sugar drops to low and many other internal reactions inside our bodies.
 
For example, when we go through adolescence, hormones are tons of fly around our body. The results? Most teenagers face acne. Once puberty is over, many people do not have acne, because the hormones are gone. What about women? During menstruation, many women, because in small groups, wait, hormones! The regulation of these hormones in the pill has worked for many women and prevented their acne.
So why do we still insist on treating acne on the outside. Why so many people find how fast you clear skin has to do with putting chemicals all over your skin? Acne will never be cured that way.

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